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SARS-DTV consortium

  (Documents from the year  2004

  when SARS-DTV research started)

 • SARS-DTV research plan

 • SARS-DTV: who we are

 • SARS-DTV leaflet

 • Contact information

  

  SARS-DTV publications

  (2004-2008)

 

  SARS-DTV final report

  (2008)

 

 

 

  Useful links

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Last update: April 2008

 

  

 

 

 

 

 

 

SARS-DTV Scientific Publications

 

Poon LLM, Leung CSW, Chan KH, Yuen KY, Guan Y, Peiris JSM (2005). Recurrent mutations associated with isolation and passage of SARS Coronavirus in cells from nonhuman primates. Journal of Medical Virology 76; 435-440.

PMID: 15977248

Poon LLM, Wong BWY, Chan KH, Ng SSF, Yuen KY, Guan Y, Peiris JSM (2005). Evaluation of real-time reverse transcriptase PCR and real-time loop-mediated amplification assays for Severe Acute Respiratory Syndrome Coronavirus detection. Journal of Clinical Microbiology, 43; 3457-3459.

PMID: 16000477

Balzarini J, Keyaerts E, Vijgen L, Egberink H, de Clerck E, van Ranst M, Printsevkaya SS, Olsufyeva EN, Solovieva SE, Preobrazhenskaya MN (2006). Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics. Antiviral Research, 72; 20-33.

PMID: 16675038

Balzarini J, Keyaerts E, Vijgen L, Vandermeer F, Stevens M, de Clercq E, Egberink H, van Ranst M (2006). Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture. Journal of Antimicrobial Chemotherapy 57; 472-481.

PMID: 16387746

Chan VSF, Chan KYK, Chen Y, Poon LLM, Cheung ANY, Zheng B, Chan KH, Mak W, Ngan HYS, Xu X, Screaton G, Tam PKH, Austyn JM, Chan LC, Yip SP, Peiris M, Khoo U, Lin CLS (2006). Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. Nature Genetics 38; 38-46.

PMID: 16369534

Dijkman R, Jebbink MF, Wilbrink B, Pyrc K, Zaaijer HL, Minor PD, Franklin S, Berkhout B, Thiel V, van der Hoek L (2006). Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes. Virology Journal, 3:106.

PMID: 17194306

Egloff MP, Malet H, Putics A, Heinonen M, Dutartre H, Frangeul A, Gruez A, Campanacci V, Cambillau C, Ziebuhr J, Ahola T, Canard B (2006). Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains. Journal of Virology, 80; 8493-8502.

PMID: 16912299

 

Gorbalenya AE, Enjuanes L, Ziebuhr J, Snijder EJ (2006) Nidovirales: evolving the largest RNA virus genome. Virus Research, 117; 17-37.

PMID: 16503362

Imbert I, Guillemot JC, Bourhis JM, Bussetta C, Coutard B, Egloff MP, Ferron F, Gorbalenya AE, Canard B (2006). A second, non-canonical RNA-dependent RNA polymerase in SARS coronavirus. EMBO Journal, 25; 4933-4942.

PMID : 17024178

Malet H, Dalle K, Bremond N, Tocque F, Blangy S, Campanacci V, Coutard B, Grisel S, Lichiere J, Lantez V, Cambillau C, Canard B, Egloff MP (2006). Expression, purification and crystallization of the SARS-CoV macro domain. Acta Crystallographica Section F Structural Biology and Crystallography Communications 62; 405-408.

PMID: 16582497

Ter Meulen J, van den Brink EN, Poon LLM, Marissen WE, Leung CSW, Cox F, Cheung CY, Bakker AQ, Bogaards JA, van Deventer E, Preiser W, Doerr HW, Chow VT, de Kruif J, Peiris JSM, Goudsmit J. (2006). Human Monoclonal Antibody Combination against SARS CoV Synergy and coverage of escape mutants. PLoS Medicine 3; e327.

PMID: 16796401

Minskaia E, Hertzig T, Gorbalenya AE, Campanacci V, Cambillau C, Canard B, Ziebuhr J (2006). Discovery of an RNA virus 3'5' exoribonuclease that is critically involved in coronavirus RNA synthesis. Proceedings of the National Academy of Sciences USA, 103; 5108-5113.

PMID: 16549795

Ricagno S, Egloff MP, Ulferts R, Coutard B, Nurizzo D, Campanacci V, Cambillau C, Ziebuhr J, Canard B (2006). Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proceedings of the National Academy of Sciences USA 103; 11892-11897.

PMID: 16882730

Ricagno S, Coutard B, Grisel S, Bremond N, Dalle K, Tocque F, Campanacci V, Lichiere J, Lantez V, Debarnot C, Cambillau C, Canard B, Egloff MP (2006). Crystallization and preliminary X-ray diffraction analysis of Nsp15 from SARS coronavirus. Acta Crystallographica Section F Structural Biology and Crystallography Communications 62; 409-411.

PMID: 16582498

Snijder EJ, van der Meer Y, Zevenhoven-Dobbe J, Onderwater JJM, van der Meulen J, Koerten HK, Mommaas AM (2006). Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. Journal of Virology 80; 5927-5940.

PMID: 16731931

 

Cervantes-Barragan L, Zust R, Weber F, Spiegel M, Lang KS, Akira S, Thiel V, Ludewig B (2007). Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood 109; 1131-1137.

PMID: 16985170

Corver J, Broer R, van Kasteren P, Spaan WJM (2007). GxxxG motif of severe acute respiratory syndrome coronavirus spike glycoprotein transmembrane domain is not involved in trimerization and is not important for entry. Journal of Virology 81; 8352-8355.

PMID: 17507478

Keyaerts E, Vijgen L, Pannecouque C, Van Damme E, Peumans W, Egberink H, Balzarini J, van Ranst M (2007). Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle. Antiviral Research 75; 179-187.

PMID: 17428553

Ziebuhr J, Schelle B, Karl N, Minskaia E, Bayer S, Siddell SG, Gorbalenya AE, Thiel V (2007). Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication. Journal of Virology 81; 3922-3932.

PMID:17251282

Züst R, Cervantes-Barragán L, Kuri T, Blakqori G, Weber F, Ludewig B, Thiel V (2007). Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS Pathogens 3; 1062-1072.

PMID: 17696607

Canard B, Joseph JS, Kuhn P (2008). International research networks in viral structural proteomics: Again, lessons from SARS. Antiviral Research 78; 47-50.

PMID 18054092

Imbert I, Snijder EJ, Dimitrova M, Guillemot JC, Lecine P, Canard B (2008). The SARS-Coronavirus PLnc domain of nsp3 as a replication/ transcription scaffolding protein. Virus Research, E-pub Feb 4.

PMID 18255185

Thiel V, Weber F (2008). Interferon and cytokine responses to SARS-coronavirus infection. Cytokine & Growth Factor Reviews, E-pub Mar 3.

PMID 18321765

Van Hemert MJ, van den Worm SHE, Knoops K, Mommaas AM, Gorbalenya AE, Snijder EJ (2008). SARS coronavirus replication/transcription complexes are enclosed by membranes and require a cytoplasmic host factor for their in vitro activity. PLoS Pathogens 4; e1000054

Decroly E, Imbert I, Coutard B, Bouvet M, Selisko B, Alvarez K, Gorbalenya AE, Snijder EJ, Canard B (2008). Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity. Journal of Virology 82, in press.

PMID 18417574